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The stimulation of mitogenic signaling pathways by N-POMC peptides
The N-terminal fragment of pro-opiomelancortin (POMC) has been shown previously to act as an adrenal mitogen. However, little is known about the molecular mechanisms by which mitogenesis is stimulated, although it has been shown that N-POMC(1–28) stimulates the ERK pathway in human H295R cells. We h...
Autores principales: | Pepper, David J., Bicknell, Andrew B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
North Holland Publishing
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651482/ https://www.ncbi.nlm.nih.gov/pubmed/18950678 http://dx.doi.org/10.1016/j.mce.2008.09.021 |
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