A Peptide Targeted Contrast Agent Specific to Fibrin-Fibronectin Complexes for Cancer Molecular Imaging with MRI

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[Image: see text] A peptide targeted contrast agent, CLT1-(Gd-DTPA), was synthesized for molecular imaging of fibronectin−fibrin complexes in tumor tissue with magnetic resonance imaging (MRI). The T(1) and T(2) relaxivities of CLT1-(Gd-DTPA) were 4.22 and 4.45 mM(−1) s(−1) at 3 T, respectively. The...

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Detalles Bibliográficos
Autores principales: Ye, Furong, Jeong, Eun-Kee, Jia, Zhanjun, Yang, Tianxin, Parker, Denis, Lu, Zheng-Rong
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651601/
https://www.ncbi.nlm.nih.gov/pubmed/19053180
http://dx.doi.org/10.1021/bc800211r

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