Cargando…

Translesion DNA Synthesis by Human DNA Polymerase η on Templates Containing a Pyrimidopurinone Deoxyguanosine Adduct, 3-(2′-Deoxy-β-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one

[Image: see text] M(1)dG (3-(2′-deoxy-β-d-erythro-pentofuranosyl)pyrimido[1,2-a]purin-10(3H)-one) lesions are mutagenic in bacterial and mammalian cells, leading to base substitutions (mostly M(1)dG to dT and M(1)dG to dA) and frameshift mutations. M(1)dG is produced endogenously through the reactio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stafford, Jennifer B., Eoff, Robert L., Kozekova, Albena, Rizzo, Carmelo J., Guengerich, F. Peter, Marnett, Lawrence J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2008
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651650/ https://www.ncbi.nlm.nih.gov/pubmed/19108641 http://dx.doi.org/10.1021/bi801591a

Ejemplares similares

Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase
por: Tomar, Rachana, et al.
Publicado: (2023)

A Cross-Sectional Study on 3-(2-Deoxy-β-D-Erythro-Pentafuranosyl)Pyrimido[1,2-α]Purin-10(3H)-One Deoxyguanosine Adducts among Woodworkers in Tuscany, Italy
por: Cellai, Filippo, et al.
Publicado: (2019)

Structural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct(,)
por: Eoff, Robert L., et al.
Publicado: (2009)

Translesion Synthesis of 2′-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases
por: Basu, Ashis K., et al.
Publicado: (2016)

Enzymatic bypass and the structural basis of miscoding opposite the DNA adduct 1,N(2)-ethenodeoxyguanosine by human DNA translesion polymerase η
por: Ghodke, Pratibha P., et al.
Publicado: (2021)

Biochemical Analysis of Six Genetic Variants of Error-Prone Human DNA Polymerase ι Involved in Translesion DNA Synthesis
por: Kim, Jinsook, et al.
Publicado: (2014)

Deaminated purine bypass by DNA polymerase η
por: Andreeva, Antonina
Publicado: (2021)

Quantitative analysis of the oxidative DNA lesion, 2,2-diamino-4-(2-deoxy-β-d-erythro-pentofuranosyl)amino]-5(2H)-oxazolone (oxazolone), in vitro and in vivo by isotope dilution-capillary HPLC-ESI-MS/MS
por: Matter, Brock, et al.
Publicado: (2006)

Replication Bypass of the trans-4-Hydroxynonenal-Derived (6S,8R,11S)-1,N(2)-Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IV
por: Banerjee, Surajit, et al.
Publicado: (2012)

Rearrangement of the (6S,8R,11S) and (6R,8S,11R) Exocyclic 1,N(2)-Deoxyguanosine Adducts of trans-4-Hydroxynonenal to N(2)-Deoxyguanosine Cyclic Hemiacetal Adducts When Placed Complementary to Cytosine in Duplex DNA
por: Huang, Hai, et al.
Publicado: (2008)

Translesion Synthesis of the N(2)-2′-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1
por: Bose, Arindam, et al.
Publicado: (2016)

The ubiquitin-binding domain of DNA polymerase η directly binds to DNA clamp PCNA and regulates translesion DNA synthesis
por: Manohar, Kodavati, et al.
Publicado: (2021)

Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis
por: Ma, Xiaolu, et al.
Publicado: (2017)

In Vitro Bypass of the Major Malondialdehyde- and Base Propenal-Derived DNA Adduct by Human Y-family DNA Polymerases κ, ι, and Rev1
por: Maddukuri, Leena, et al.
Publicado: (2010)

Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres
por: Garcia-Exposito, Laura, et al.
Publicado: (2016)

Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity
por: Mentegari, Elisa, et al.
Publicado: (2017)

A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ
por: Yamanaka, Kinrin, et al.
Publicado: (2012)

Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis
por: Peddu, Chandana, et al.
Publicado: (2018)

γ-Hydroxy-1,N(2)-propano-2′-deoxyguanosine DNA Adduct Conjugates the N-Terminal Amine of the KWKK Peptide via a Carbinolamine Linkage
por: Huang, Hai, et al.
Publicado: (2011)

The C-terminal region of translesion synthesis DNA polymerase η is partially unstructured and has high conformational flexibility
por: Powers, Kyle T, et al.
Publicado: (2018)

Enzymatic bypass of an N(6)-deoxyadenosine DNA–ethylene dibromide–peptide cross-link by translesion DNA polymerases
por: Ghodke, Pratibha P., et al.
Publicado: (2021)

DNA polymerases η and κ bypass N(2)-guanine-O(6)-alkylguanine DNA alkyltransferase cross-linked DNA-peptides
por: Ghodke, Pratibha P., et al.
Publicado: (2021)

Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage
por: Eoff, Robert L., et al.
Publicado: (2010)

Role of the ubiquitin-binding domain of Polη in Rad18-independent translesion DNA synthesis in human cell extracts
por: Schmutz, Valérie, et al.
Publicado: (2010)

Translesion synthesis DNA polymerase η exhibits a specific RNA extension activity and a transcription-associated function
por: Gali, Vamsi K., et al.
Publicado: (2017)

Translesion DNA Polymerases and Cancer
por: Makridakis, Nick M., et al.
Publicado: (2012)

DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8–2′-deoxyguanosine adduct of the dietary mutagen IQ in human cells
por: Bose, Arindam, et al.
Publicado: (2015)

Erythro-Melalgia
Publicado: (1891)

The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA–topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts
por: Dexheimer, Thomas S., et al.
Publicado: (2008)

Expression of DNA Translesion Synthesis Polymerase η in Head and Neck Squamous Cell Cancer Predicts Resistance to Gemcitabine and Cisplatin-Based Chemotherapy
por: Zhou, Wendi, et al.
Publicado: (2013)

DNA Polymerase β Gap-Filling Translesion DNA Synthesis
por: Chary, Parvathi, et al.
Publicado: (2012)

A highly conserved Tyrosine residue of family B DNA polymerases contributes to dictate translesion synthesis past 8-oxo-7,8-dihydro-2′-deoxyguanosine
por: de Vega, Miguel, et al.
Publicado: (2007)

Translesion DNA synthesis in the context of cancer research
por: Knobel, Philip A, et al.
Publicado: (2011)

Lesion orientation of O(4)-alkylthymidine influences replication by human DNA polymerase η
por: O'Flaherty, D. K., et al.
Publicado: (2016)

The effect of the 2-amino group of 7,8-dihydro-8-oxo-2′-deoxyguanosine on translesion synthesis and duplex stability
por: Oka, Natsuhisa, et al.
Publicado: (2005)

Plant organellar DNA polymerases are replicative and translesion DNA synthesis polymerases
por: Baruch-Torres, Noe, et al.
Publicado: (2017)

Stalling of Eukaryotic Translesion DNA Polymerases at DNA-Protein Cross-Links
por: Yudkina, Anna V., et al.
Publicado: (2022)

Uncovering the reactive nature of 4-deoxy-l-erythro-5-hexoseulose uronate for the utilization of alginate, a promising marine biopolymer
por: Nakata, Shota, et al.
Publicado: (2019)

4-Deoxy-l-erythro-5-hexoseulose Uronate (DEH) and DEH Reductase: Key Molecule and Enzyme for the Metabolism and Utilization of Alginate
por: Kawai, Shigeyuki, et al.
Publicado: (2022)

Inhibition of translesion DNA polymerase by archaeal reverse gyrase
por: Valenti, Anna, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_srq0orridp1leeb501goanfvhj