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Distributed Drug Discovery, Part 2: Global Rehearsal of Alkylating Agents for the Synthesis of Resin-Bound Unnatural Amino Acids and Virtual D(3) Catalog Construction

[Image: see text] Distributed Drug Discovery (D(3)) proposes solving large drug discovery problems by breaking them into smaller units for processing at multiple sites. A key component of the synthetic and computational stages of D(3) is the global rehearsal of prospective reagents and their subsequ...

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Detalles Bibliográficos
Autores principales: Scott, William L., Alsina, Jordi, Audu, Christopher O., Babaev, Evgenii, Cook, Linda, Dage, Jeffery L., Goodwin, Lawrence A., Martynow, Jacek G., Matosiuk, Dariusz, Royo, Miriam, Smith, Judith G., Strong, Andrew T., Wickizer, Kirk, Woerly, Eric M., Zhou, Ziniu, O’Donnell, Martin J.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651687/
https://www.ncbi.nlm.nih.gov/pubmed/19105725
http://dx.doi.org/10.1021/cc800184v