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Concurrent Binding of Complexin and Synaptotagmin to Liposome-Embedded SNARE Complexes
[Image: see text] Synaptotagmin and complexin regulate SNARE-mediated synaptic vesicle exocytosis. It has been proposed that complexin clamps membrane fusion and that Ca(2+)-synaptotagmin displaces complexin from SNARE complexes to relieve this clamping activity. Using a reconstituted system, we dem...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651691/ https://www.ncbi.nlm.nih.gov/pubmed/19128031 http://dx.doi.org/10.1021/bi801962d |