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Imaging of the unusual pediatric ‘blastomas’

‘Blastomas’ are tumors virtually unique to childhood. Controversy surrounds their nomenclature and there is no globally accepted classification. They are thought to arise from immature, primitive tissues that present persistent embryonal elements on histology, affect a younger pediatric population a...

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Detalles Bibliográficos
Autores principales: Papaioannou, Georgia, Sebire, Neil J., McHugh, Kieran
Formato: Texto
Lenguaje:English
Publicado: e-Med 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651735/
https://www.ncbi.nlm.nih.gov/pubmed/19237343
http://dx.doi.org/10.1102/1470-7330.2009.0001
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author Papaioannou, Georgia
Sebire, Neil J.
McHugh, Kieran
author_facet Papaioannou, Georgia
Sebire, Neil J.
McHugh, Kieran
author_sort Papaioannou, Georgia
collection PubMed
description ‘Blastomas’ are tumors virtually unique to childhood. Controversy surrounds their nomenclature and there is no globally accepted classification. They are thought to arise from immature, primitive tissues that present persistent embryonal elements on histology, affect a younger pediatric population and are usually malignant. The ‘commoner’ blastomas (neuroblastoma, nephroblastoma, hepatoblastoma, medulloblastoma) account for approximately 25% of solid tumors in the pediatric age range. We present examples of the more unusual blastematous pediatric tumors (lipoblastoma, osteoblastoma, chondroblastoma, hemangioblastoma, gonadoblastoma, sialoblastoma, pleuropulmonary blastoma, pancreatoblastoma, pineoblastoma, and medullomyoblastoma) that were recorded in our institution. Although these rare types of blastomas individually account for <1% of pediatric malignancies, collectively they may be responsible for up to 5% of pediatric tumors in a given population of young children. Imaging is often non-specific but plays an important role in their identification, management and follow-up. Some characteristic imaging features at diagnosis, encountered in cases diagnosed and treated in our institution, are described and reviewed.
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spelling pubmed-26517352009-03-05 Imaging of the unusual pediatric ‘blastomas’ Papaioannou, Georgia Sebire, Neil J. McHugh, Kieran Cancer Imaging Review Article ‘Blastomas’ are tumors virtually unique to childhood. Controversy surrounds their nomenclature and there is no globally accepted classification. They are thought to arise from immature, primitive tissues that present persistent embryonal elements on histology, affect a younger pediatric population and are usually malignant. The ‘commoner’ blastomas (neuroblastoma, nephroblastoma, hepatoblastoma, medulloblastoma) account for approximately 25% of solid tumors in the pediatric age range. We present examples of the more unusual blastematous pediatric tumors (lipoblastoma, osteoblastoma, chondroblastoma, hemangioblastoma, gonadoblastoma, sialoblastoma, pleuropulmonary blastoma, pancreatoblastoma, pineoblastoma, and medullomyoblastoma) that were recorded in our institution. Although these rare types of blastomas individually account for <1% of pediatric malignancies, collectively they may be responsible for up to 5% of pediatric tumors in a given population of young children. Imaging is often non-specific but plays an important role in their identification, management and follow-up. Some characteristic imaging features at diagnosis, encountered in cases diagnosed and treated in our institution, are described and reviewed. e-Med 2009-02-02 /pmc/articles/PMC2651735/ /pubmed/19237343 http://dx.doi.org/10.1102/1470-7330.2009.0001 Text en © 2009 International Cancer Imaging Society
spellingShingle Review Article
Papaioannou, Georgia
Sebire, Neil J.
McHugh, Kieran
Imaging of the unusual pediatric ‘blastomas’
title Imaging of the unusual pediatric ‘blastomas’
title_full Imaging of the unusual pediatric ‘blastomas’
title_fullStr Imaging of the unusual pediatric ‘blastomas’
title_full_unstemmed Imaging of the unusual pediatric ‘blastomas’
title_short Imaging of the unusual pediatric ‘blastomas’
title_sort imaging of the unusual pediatric ‘blastomas’
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651735/
https://www.ncbi.nlm.nih.gov/pubmed/19237343
http://dx.doi.org/10.1102/1470-7330.2009.0001
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