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An insulator element 3′ to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells

Regulation of expression of the CFTR gene is poorly understood. Elements within the basal promoter of the gene do not fully explain CFTR expression patterns, suggesting that cis-regulatory elements are located elsewhere, either within the locus or in adjacent chromatin. We previously mapped DNase I...

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Detalles Bibliográficos
Autores principales:	Blackledge, Neil P., Ott, Christopher J., Gillen, Austin E., Harris, Ann
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651798/ https://www.ncbi.nlm.nih.gov/pubmed/19129223 http://dx.doi.org/10.1093/nar/gkn1056

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