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Mechanism of DNA flexibility enhancement by HMGB proteins
The mechanism by which sequence non-specific DNA-binding proteins enhance DNA flexibility is studied by examining complexes of double-stranded DNA with the high mobility group type B proteins HMGB2 (Box A) and HMGB1 (Box A+B) using atomic force microscopy. DNA end-to-end distances and local DNA bend...
Autores principales: | Zhang, Jingyun, McCauley, Micah J., Maher, L. James, Williams, Mark C., Israeloff, N. E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651801/ https://www.ncbi.nlm.nih.gov/pubmed/19129233 http://dx.doi.org/10.1093/nar/gkn1011 |
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