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Mutually exclusive STAT1 modifications identified by Ubc9/substrate dimerization-dependent SUMOylation
Post-translational modifications control the physiological activity of the signal transducer and activator of transcription STAT1. While phosphorylation at tyrosine Y701 is a prerequisite for STAT1 dimerization, its SUMOylation represses the transcriptional activity. Recently, we have demonstrated t...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651805/ https://www.ncbi.nlm.nih.gov/pubmed/19174562 http://dx.doi.org/10.1093/nar/gkp020 |