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AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts

BACKGROUND: Pluripotency, the property of a cell to differentiate into all cellular types of a given organism, is central to the development of stem cell-based therapies and regenerative medicine. Stem cell pluripotency is the result of the orchestrated activation of a complex transcriptional networ...

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Detalles Bibliográficos
Autores principales:	Adamo, Luigi, Zhang, Yuzhi, García-Cardeña, Guillermo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651871/ https://www.ncbi.nlm.nih.gov/pubmed/19216758 http://dx.doi.org/10.1186/1471-2210-9-2

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