Rapid intracerebroventricular delivery of Cu-DOTA-etanercept after peripheral administration demonstrated by PET imaging

BACKGROUND: The cytokines interleukin-1 and tumor necrosis factor (TNF), and the cytokine blocker interleukin-1 receptor antagonist, all have been demonstrated to enter the cerebrospinal fluid (CSF) following peripheral administration. Recent reports of rapid clinical improvement in patients with Al...

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Detalles Bibliográficos
Autores principales: Tobinick, Edward L, Chen, Kai, Chen, Xiaoyuan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651903/
https://www.ncbi.nlm.nih.gov/pubmed/19284700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651903/
https://www.ncbi.nlm.nih.gov/pubmed/19284700

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