Cargando…

α-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress

PURPOSE: To investigate the susceptibility of retinal pigment epithelium (RPE) from αA (-/-) and αB (-/-) mice to oxidative stress, and the subcellular changes of αA and αB-crystallins under oxidative stress. METHODS: The effect of hydrogen peroxide (H(2)O(2)) on apoptosis in RPE from αA (-/-), αB (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yaung, Jennifer, Jin, Manlin, Barron, Ernesto, Spee, Christine, Wawrousek, Eric F., Kannan, Ram, Hinton, David R.
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Vision 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652021/ https://www.ncbi.nlm.nih.gov/pubmed/17438522

Ejemplares similares

αB Crystallin Is Apically Secreted within Exosomes by Polarized Human Retinal Pigment Epithelium and Provides Neuroprotection to Adjacent Cells
por: Sreekumar, Parameswaran G., et al.
Publicado: (2010)

Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy
por: Ishikawa, Keijiro, et al.
Publicado: (2015)

Protection of Retina by αB Crystallin in Sodium Iodate Induced Retinal Degeneration
por: Zhou, Peng, et al.
Publicado: (2014)

Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells
por: Wang, Mo, et al.
Publicado: (2019)

Neutrophils Compromise Retinal Pigment Epithelial Barrier Integrity
por: Zhou, Jiehao, et al.
Publicado: (2010)

OUTER RETINAL TUBULATION IN BIETTI CRYSTALLINE DYSTROPHY ASSOCIATED WITH THE RETINAL PIGMENT EPITHELIUM ATROPHY
por: Wang, Yusong, et al.
Publicado: (2023)

A selective cyclic integrin antagonist blocks the integrin receptors α(v)β(3 )and α(v)β(5 )and inhibits retinal pigment epithelium cell attachment, migration and invasion
por: Hoffmann, Stephan, et al.
Publicado: (2005)

Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration
por: Sonoda, Shozo, et al.
Publicado: (2009)

Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux
por: Sreekumar, Parameswaran G., et al.
Publicado: (2012)

Morphological characterization of the AlphaA- and AlphaB-crystallin double knockout mouse lens
por: Boyle, Daniel L, et al.
Publicado: (2003)

Evaluation of focal damage in the retinal pigment epithelium layer in serous retinal pigment epithelium detachment
por: Miura, Masahiro, et al.
Publicado: (2019)

Translocation of the retinal pigment epithelium and formation of sub-retinal pigment epithelium deposit induced by subretinal deposit
por: Zhao, Lian, et al.
Publicado: (2007)

Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice
por: Sreekumar, Parameswaran Gangadharan, et al.
Publicado: (2023)

Setting Eyes on the Retinal Pigment Epithelium
por: Moreno-Marmol, Tania, et al.
Publicado: (2018)

Functions and Diseases of the Retinal Pigment Epithelium
por: Yang, Song, et al.
Publicado: (2021)

Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium
por: Zhang, Youwen, et al.
Publicado: (2010)

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models
por: Sugita, Sunao, et al.
Publicado: (2017)

Impact of drusen and drusenoid retinal pigment epithelium elevation size and structure on the integrity of the retinal pigment epithelium layer
por: Schlanitz, Ferdinand, et al.
Publicado: (2019)

Common clinical features of unilateral retinal pigment epithelium dysgenesis and combined hamartoma of the retina and retinal pigment epithelium
por: Zhu, Zhe, et al.
Publicado: (2022)

Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells
por: Sreekumar, Parameswaran G, et al.
Publicado: (2020)

In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells
por: Holmgaard, Andreas, et al.
Publicado: (2017)

Protrusion of KCNJ13 Gene Knockout Retinal Pigment Epithelium Due to Oxidative Stress–Induced Cell Death
por: Kanzaki, Yuki, et al.
Publicado: (2022)

Retinal sensitivity and photoreceptor arrangement changes secondary to congenital simple hamartoma of retinal pigment epithelium
por: Rodrigues, M. W., et al.
Publicado: (2019)

αB-Crystallin Peptide Fused with Elastin-like Polypeptide: Intracellular Activity in Retinal Pigment Epithelial Cells Challenged with Oxidative Stress †
por: Attia, Sara Aly, et al.
Publicado: (2023)

Mechanisms of Epithelial-Mesenchymal Transition and Prevention of Dispase-Induced PVR by Delivery of an Antioxidant αB Crystallin Peptide †
por: Wada, Iori, et al.
Publicado: (2022)

Components of the cytoskeleton in the retinal pigmented epithelium of the chick
Publicado: (1985)

Retinal Pigment Epithelium Derived Stem Cells
por: Hiscott, Paul, et al.
Publicado: (2009)

Characterization of the retinal pigment epithelium in Friedreich ataxia
por: Crombie, Duncan E., et al.
Publicado: (2015)

Retinal pigment epithelium changes in Kartagener syndrome
por: Garcia, Maria D., et al.
Publicado: (2018)

Simple Congenital Hamartoma of the Retinal Pigment Epithelium
por: Nakatsuka, Austin S., et al.
Publicado: (2020)

Circadian Regulation of Retinal Pigment Epithelium Function
por: Baba, Kenkichi, et al.
Publicado: (2022)

Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium.
por: Bennis, A., et al.
Publicado: (2017)

α-Synuclein impairs ferritinophagy in the retinal pigment epithelium: Implications for retinal iron dyshomeostasis in Parkinson’s disease
por: Baksi, Shounak, et al.
Publicado: (2017)

Reprogramming of the chick retinal pigmented epithelium after retinal injury
por: Luz-Madrigal, Agustin, et al.
Publicado: (2014)

Involvement of the Retinal Pigment Epithelium in the Development of Retinal Lattice Degeneration
por: Mizuno, Hiroshi, et al.
Publicado: (2020)

Shared Features in Retinal Disorders With Involvement of Retinal Pigment Epithelium
por: Sparrow, Janet R., et al.
Publicado: (2021)

Retinal Pigment Epithelium Remodeling in Mouse Models of Retinitis Pigmentosa
por: Napoli, Debora, et al.
Publicado: (2021)

Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response
por: Valapala, Mallika, et al.
Publicado: (2014)

Targeting of exon VI-skipping human RGR-opsin to the plasma membrane of pigment epithelium and co-localization with terminal complement complex C5b-9
por: Kochounian, Harold, et al.
Publicado: (2016)

Cytoplasmic and Nuclear Anti-Apoptotic Roles of αB-Crystallin in Retinal Pigment Epithelial Cells
por: Jeong, Woo Jin, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_n64us5kc60bo4hfedmfatb4lqf