Severe Plasmodium falciparum Malaria Is Associated with Circulating Ultra-Large von Willebrand Multimers and ADAMTS13 Inhibition

Plasmodium falciparum infection results in adhesion of infected erythrocytes to blood vessel endothelium, and acute endothelial cell activation, together with sequestration of platelets and leucocytes. We have previously shown that patients with severe infection or fulminant cerebral malaria have si...

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Detalles Bibliográficos
Autores principales: Larkin, Deirdre, de Laat, Bas, Jenkins, P. Vince, Bunn, James, Craig, Alister G., Terraube, Virginie, Preston, Roger J. S., Donkor, Cynthia, Grau, George E., van Mourik, Jan A., O'Donnell, James S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652105/
https://www.ncbi.nlm.nih.gov/pubmed/19300493
http://dx.doi.org/10.1371/journal.ppat.1000349

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