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F- and G-Actin Concentrations in Lamellipodia of Moving Cells

Cells protrude by polymerizing monomeric (G) into polymeric (F) actin at the tip of the lamellipodium. Actin filaments are depolymerized towards the rear of the lamellipodium in a treadmilling process, thereby supplementing a G-actin pool for a new round of polymerization. In this scenario the conce...

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Detalles Bibliográficos
Autores principales: Koestler, Stefan A., Rottner, Klemens, Lai, Frank, Block, Jennifer, Vinzenz, Marlene, Small, J. Victor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652108/
https://www.ncbi.nlm.nih.gov/pubmed/19277198
http://dx.doi.org/10.1371/journal.pone.0004810