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Water-Soluble Fullerene (C(60)) Derivatives as Nonviral Gene-Delivery Vectors

[Image: see text] A new class of water-soluble C(60) transfecting agents has been prepared using Hirsch−Bingel chemistry and assessed for their ability to act as gene-delivery vectors in vitro. In an effort to elucidate the relationship between the hydrophobicity of the fullerene core, the hydrophil...

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Detalles Bibliográficos
Autores principales: Sitharaman, Balaji, Zakharian, Tatiana Y., Saraf, Anita, Misra, Preeti, Ashcroft, Jared, Pan, Su, Pham, Quynh P., Mikos, Antonios G., Wilson, Lon J., Engler, David A.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652357/
https://www.ncbi.nlm.nih.gov/pubmed/18505267
http://dx.doi.org/10.1021/mp700106w