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Transcriptional Infidelity Promotes Heritable Phenotypic Change in a Bistable Gene Network
Bistable epigenetic switches are fundamental for cell fate determination in unicellular and multicellular organisms. Regulatory proteins associated with bistable switches are often present in low numbers and subject to molecular noise. It is becoming clear that noise in gene expression can influence...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652393/ https://www.ncbi.nlm.nih.gov/pubmed/19243224 http://dx.doi.org/10.1371/journal.pbio.1000044 |