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Diversity Synthesis of Complex Pyridines Yields a Probe of a Neurotrophic Signaling Pathway
[Image: see text] Recognizing the value of including complex pyridines in small-molecule screening collections, we developed a previously unexplored [2 + 2 + 2]-cycloaddition of silyl-tethered diynes with nitriles. The tether provides high regioselectivity, while the solvent THF allows catalytic CpC...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652409/ https://www.ncbi.nlm.nih.gov/pubmed/18510333 http://dx.doi.org/10.1021/ol8004936 |