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The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea
BACKGROUND: We undertook a population genetics analysis of the tsetse fly Glossina palpalis gambiensis, a major vector of sleeping sickness in West Africa, using microsatellite and mitochondrial DNA markers. Our aims were to estimate effective population size and the degree of isolation between coas...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652410/ https://www.ncbi.nlm.nih.gov/pubmed/19290038 http://dx.doi.org/10.1371/journal.pntd.0000392 |
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author | Solano, Philippe Ravel, Sophie Bouyer, Jeremy Camara, Mamadou Kagbadouno, Moise S. Dyer, Naomi Gardes, Laetitia Herault, Damien Donnelly, Martin J. De Meeûs, Thierry |
author_facet | Solano, Philippe Ravel, Sophie Bouyer, Jeremy Camara, Mamadou Kagbadouno, Moise S. Dyer, Naomi Gardes, Laetitia Herault, Damien Donnelly, Martin J. De Meeûs, Thierry |
author_sort | Solano, Philippe |
collection | PubMed |
description | BACKGROUND: We undertook a population genetics analysis of the tsetse fly Glossina palpalis gambiensis, a major vector of sleeping sickness in West Africa, using microsatellite and mitochondrial DNA markers. Our aims were to estimate effective population size and the degree of isolation between coastal sites on the mainland of Guinea and Loos Islands. The sampling locations encompassed Dubréka, the area with the highest Human African Trypanosomosis (HAT) prevalence in West Africa, mangrove and savannah sites on the mainland, and two islands, Fotoba and Kassa, within the Loos archipelago. These data are discussed with respect to the feasibility and sustainability of control strategies in those sites currently experiencing, or at risk of, sleeping sickness. PRINCIPAL FINDINGS: We found very low migration rates between sites except between those sampled around the Dubréka area that seems to contain a widely dispersed and panmictic population. In the Kassa island samples, various effective population size estimates all converged on surprisingly small values (10<N(e)<30) that suggest either a recent bottleneck, and/or other biological or ecological factors such as strong variance in the reproductive success of individuals. CONCLUSION/SIGNIFICANCE: Whatever their origin, the small effective population sizes suggest high levels of inbreeding in tsetse flies within the island samples in marked contrast to the large diffuse deme in Dubréka zones. We discuss how these genetic results suggest that different tsetse control strategies should be applied on the mainland and islands. |
format | Text |
id | pubmed-2652410 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-26524102009-03-17 The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea Solano, Philippe Ravel, Sophie Bouyer, Jeremy Camara, Mamadou Kagbadouno, Moise S. Dyer, Naomi Gardes, Laetitia Herault, Damien Donnelly, Martin J. De Meeûs, Thierry PLoS Negl Trop Dis Research Article BACKGROUND: We undertook a population genetics analysis of the tsetse fly Glossina palpalis gambiensis, a major vector of sleeping sickness in West Africa, using microsatellite and mitochondrial DNA markers. Our aims were to estimate effective population size and the degree of isolation between coastal sites on the mainland of Guinea and Loos Islands. The sampling locations encompassed Dubréka, the area with the highest Human African Trypanosomosis (HAT) prevalence in West Africa, mangrove and savannah sites on the mainland, and two islands, Fotoba and Kassa, within the Loos archipelago. These data are discussed with respect to the feasibility and sustainability of control strategies in those sites currently experiencing, or at risk of, sleeping sickness. PRINCIPAL FINDINGS: We found very low migration rates between sites except between those sampled around the Dubréka area that seems to contain a widely dispersed and panmictic population. In the Kassa island samples, various effective population size estimates all converged on surprisingly small values (10<N(e)<30) that suggest either a recent bottleneck, and/or other biological or ecological factors such as strong variance in the reproductive success of individuals. CONCLUSION/SIGNIFICANCE: Whatever their origin, the small effective population sizes suggest high levels of inbreeding in tsetse flies within the island samples in marked contrast to the large diffuse deme in Dubréka zones. We discuss how these genetic results suggest that different tsetse control strategies should be applied on the mainland and islands. Public Library of Science 2009-03-17 /pmc/articles/PMC2652410/ /pubmed/19290038 http://dx.doi.org/10.1371/journal.pntd.0000392 Text en Solano et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Solano, Philippe Ravel, Sophie Bouyer, Jeremy Camara, Mamadou Kagbadouno, Moise S. Dyer, Naomi Gardes, Laetitia Herault, Damien Donnelly, Martin J. De Meeûs, Thierry The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea |
title | The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea |
title_full | The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea |
title_fullStr | The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea |
title_full_unstemmed | The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea |
title_short | The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea |
title_sort | population structure of glossina palpalis gambiensis from island and continental locations in coastal guinea |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652410/ https://www.ncbi.nlm.nih.gov/pubmed/19290038 http://dx.doi.org/10.1371/journal.pntd.0000392 |
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