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An Epstein-Barr Virus Anti-Apoptotic Protein Constitutively Expressed in Transformed Cells and Implicated in Burkitt Lymphomagenesis: The Wp/BHRF1 Link

Two factors contribute to Burkitt lymphoma (BL) pathogenesis, a chromosomal translocation leading to c-myc oncogene deregulation and infection with Epstein-Barr virus (EBV). Although the virus has B cell growth–transforming ability, this may not relate to its role in BL since many of the transformin...

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Detalles Bibliográficos
Autores principales: Kelly, Gemma L., Long, Heather M., Stylianou, Julianna, Thomas, Wendy A., Leese, Alison, Bell, Andrew I., Bornkamm, Georg W., Mautner, Josef, Rickinson, Alan B., Rowe, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652661/
https://www.ncbi.nlm.nih.gov/pubmed/19283066
http://dx.doi.org/10.1371/journal.ppat.1000341