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Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia
AIMS: Sepsis-associated cardiac dysfunction represents an intrinsic impairment of cardiomyocyte function due in part to a decrease in myofilament Ca(2+) sensitivity associated with a sustained increase in cardiac troponin I (cTnI) phosphorylation at Ser23/24. Dephosphorylation of cTnI is under regul...
Autores principales: | Marshall, Melanie, Anilkumar, Narayana, Layland, Joanne, Walker, Simon J., Kentish, Jonathan C., Shah, Ajay M., Cave, Alison C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652740/ https://www.ncbi.nlm.nih.gov/pubmed/19201758 http://dx.doi.org/10.1093/cvr/cvp037 |
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