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Exploring the mechanism of tryptophan 2,3-dioxygenase

The haem proteins TDO (tryptophan 2,3-dioxygenase) and IDO (indoleamine 2,3-dioxygenase) are specific and powerful oxidation catalysts that insert one molecule of dioxygen into L-tryptophan in the first and rate-limiting step in the kynurenine pathway. Recent crystallographic and biochemical analyse...

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Detalles Bibliográficos
Autores principales:	Thackray, Sarah J., Mowat, Christopher G., Chapman, Stephen K.
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2008
Materias:	Biochemical Society Focused Meetings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652831/ https://www.ncbi.nlm.nih.gov/pubmed/19021508 http://dx.doi.org/10.1042/BST0361120

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