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Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type

BACKGROUND: HIV-1 Gag proteins are essential for virion assembly and viral replication in newly infected cells. Gag proteins are also strong determinants of viral infectivity; immune escape mutations in the Gag capsid (CA) protein can markedly reduce viral fitness, and interactions of CA with host p...

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Detalles Bibliográficos
Autores principales: Matsuoka, Saori, Dam, Elisabeth, Lecossier, Denise, Clavel, François, Hance, Allan J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653016/
https://www.ncbi.nlm.nih.gov/pubmed/19254360
http://dx.doi.org/10.1186/1742-4690-6-21

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