Unbalanced chromosome 1 abnormalities leading to partial trisomy 1q in four infants with Down syndrome and acute megakaryocytic leukemia

BACKGROUND: Children with Down syndrome (DS) have an increased risk of childhood acute leukemia, especially acute megakaryoblastic leukemia (AMKL) also called acute myeloid leukemia (AML) type M7. Here four yet unreported infants with such malignancies are reported. RESULTS: An unbalanced translocat...

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Detalles Bibliográficos
Autores principales: Silva, Maria Luiza Macedo, do Socorro Pombo-de-Oliveira, Maria, Raimondi, Susana C, Mkrtchyan, Hasmik, Abdelhay, Eliana, de Figueiredo, Amanda Faria, de Souza, Mariana Tavares, Garcia, Daniela Ribeiro Ney, de Ventura, Eliane Maria Soares, de Sousa, Adriana Martins, Liehr, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653040/
https://www.ncbi.nlm.nih.gov/pubmed/19228396
http://dx.doi.org/10.1186/1755-8166-2-7

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