Pleiotropic effects in Eya3 knockout mice

BACKGROUND: In Drosophila, mutations in the gene eyes absent (eya) lead to severe defects in eye development. The functions of its mammalian orthologs Eya1-4 are only partially understood and no mouse model exists for Eya3. Therefore, we characterized the phenotype of a new Eya3 knockout mouse mutan...

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Detalles Bibliográficos
Autores principales: Söker, Torben, Dalke, Claudia, Puk, Oliver, Floss, Thomas, Becker, Lore, Bolle, Ines, Favor, Jack, Hans, Wolfgang, Hölter, Sabine M, Horsch, Marion, Kallnik, Magdalena, Kling, Eva, Moerth, Corinna, Schrewe, Anja, Stigloher, Christian, Topp, Stefanie, Gailus-Durner, Valerie, Naton, Beatrix, Beckers, Johannes, Fuchs, Helmut, Ivandic, Boris, Klopstock, Thomas, Schulz, Holger, Wolf, Eckhard, Wurst, Wolfgang, Bally-Cuif, Laure, de Angelis, Martin Hrabé, Graw, Jochen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653502/
https://www.ncbi.nlm.nih.gov/pubmed/19102749
http://dx.doi.org/10.1186/1471-213X-8-118

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