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Telomerase prevents accelerated senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts

Fibroblasts derived from glucose-6-phosphate dehydrogenase (G6PD)-deficient patients display retarded growth and accelerated cellular senescence that is attributable to increased accumulation of oxidative DNA damage and increased sensitivity to oxidant-induced senescence, but not to accelerated telo...

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Detalles Bibliográficos
Autores principales: Wu, Yi-Hsuan, Cheng, Mei-Ling, Ho, Hung-Yao, Chiu, Daniel Tsun-Yee, Wang, Tzu-Chien V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653519/
https://www.ncbi.nlm.nih.gov/pubmed/19272180
http://dx.doi.org/10.1186/1423-0127-16-18