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Telomerase prevents accelerated senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts
Fibroblasts derived from glucose-6-phosphate dehydrogenase (G6PD)-deficient patients display retarded growth and accelerated cellular senescence that is attributable to increased accumulation of oxidative DNA damage and increased sensitivity to oxidant-induced senescence, but not to accelerated telo...
Autores principales: | Wu, Yi-Hsuan, Cheng, Mei-Ling, Ho, Hung-Yao, Chiu, Daniel Tsun-Yee, Wang, Tzu-Chien V |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653519/ https://www.ncbi.nlm.nih.gov/pubmed/19272180 http://dx.doi.org/10.1186/1423-0127-16-18 |
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