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Regulation of multi-organ inflammation in the regulatory T cell-deficient scurfy mice
Scurfy mice display the most severe form of multi-organ inflammation due to total lack of the CD4(+)Foxp3(+ )regulatory T cells (Treg) resulted from a mutation of the X-linked transcription factor Foxp3. A large repertoire of Treg-suppressible, inflammation-inducing T cells was demonstrated by adopt...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653523/ https://www.ncbi.nlm.nih.gov/pubmed/19272184 http://dx.doi.org/10.1186/1423-0127-16-20 |