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DNA Methylation Analysis of Chromosome 21 Gene Promoters at Single Base Pair and Single Allele Resolution

Differential DNA methylation is an essential epigenetic signal for gene regulation, development, and disease processes. We mapped DNA methylation patterns of 190 gene promoter regions on chromosome 21 using bisulfite conversion and subclone sequencing in five human cell types. A total of 28,626 subc...

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Detalles Bibliográficos
Autores principales:	Zhang, Yingying, Rohde, Christian, Tierling, Sascha, Jurkowski, Tomasz P., Bock, Christoph, Santacruz, Diana, Ragozin, Sergey, Reinhardt, Richard, Groth, Marco, Walter, Jörn, Jeltsch, Albert
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653639/ https://www.ncbi.nlm.nih.gov/pubmed/19325872 http://dx.doi.org/10.1371/journal.pgen.1000438

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