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Two-Dimensional Electrophoresis of Tau Mutants Reveals Specific Phosphorylation Pattern Likely Linked to Early Tau Conformational Changes

The role of Tau phosphorylation in neurofibrillary degeneration linked to Alzheimer's disease remains to be established. While transgenic mice based on FTDP-17 Tau mutations recapitulate hallmarks of neurofibrillary degeneration, cell models could be helpful for exploratory studies on molecular...

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Detalles Bibliográficos
Autores principales:	Bretteville, Alexis, Ando, Kunie, Ghestem, Antoine, Loyens, Anne, Bégard, Séverine, Beauvillain, Jean-Claude, Sergeant, Nicolas, Hamdane, Malika, Buée, Luc
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653646/ https://www.ncbi.nlm.nih.gov/pubmed/19290042 http://dx.doi.org/10.1371/journal.pone.0004843

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