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Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide derivatives and the effect of RNA silencing on intracellular metabolism

Intracellular generation of the photosensitiser, protoporphyrin IX, from a series of dipeptide derivatives of the haem precursor, 5-aminolaevulinic acid (ALA), was investigated in transformed PAM212 murine keratinocytes, together with studies of their intracellular metabolism. Porphyrin production w...

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Detalles Bibliográficos
Autores principales:	Bourré, L, Giuntini, F, Eggleston, I M, Wilson, M, MacRobert, A J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653757/ https://www.ncbi.nlm.nih.gov/pubmed/19240715 http://dx.doi.org/10.1038/sj.bjc.6604928

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