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Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997

Using archived tumours, those from 1984–1986 and 1996–1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices, but could still influence survival.

Detalles Bibliográficos
Autores principales: Brown, S B F, Mallon, E A, Edwards, J, Campbell, F M, McGlynn, L M, Elsberger, B, Cooke, T G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653769/
https://www.ncbi.nlm.nih.gov/pubmed/19223901
http://dx.doi.org/10.1038/sj.bjc.6604934
Descripción
Sumario:Using archived tumours, those from 1984–1986 and 1996–1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices, but could still influence survival.