Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997

Using archived tumours, those from 1984–1986 and 1996–1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices, but could still influence survival.

Detalles Bibliográficos
Autores principales: Brown, S B F, Mallon, E A, Edwards, J, Campbell, F M, McGlynn, L M, Elsberger, B, Cooke, T G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653769/
https://www.ncbi.nlm.nih.gov/pubmed/19223901
http://dx.doi.org/10.1038/sj.bjc.6604934
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author Brown, S B F
Mallon, E A
Edwards, J
Campbell, F M
McGlynn, L M
Elsberger, B
Cooke, T G
author_facet Brown, S B F
Mallon, E A
Edwards, J
Campbell, F M
McGlynn, L M
Elsberger, B
Cooke, T G
author_sort Brown, S B F
collection PubMed
description Using archived tumours, those from 1984–1986 and 1996–1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices, but could still influence survival.
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spelling pubmed-26537692010-03-10 Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997 Brown, S B F Mallon, E A Edwards, J Campbell, F M McGlynn, L M Elsberger, B Cooke, T G Br J Cancer Epidemiology Using archived tumours, those from 1984–1986 and 1996–1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices, but could still influence survival. Nature Publishing Group 2009-03-10 2009-02-17 /pmc/articles/PMC2653769/ /pubmed/19223901 http://dx.doi.org/10.1038/sj.bjc.6604934 Text en Copyright © 2009 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiology
Brown, S B F
Mallon, E A
Edwards, J
Campbell, F M
McGlynn, L M
Elsberger, B
Cooke, T G
Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997
title Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997
title_full Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997
title_fullStr Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997
title_full_unstemmed Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997
title_short Is the biology of breast cancer changing? A study of hormone receptor status 1984–1986 and 1996–1997
title_sort is the biology of breast cancer changing? a study of hormone receptor status 1984–1986 and 1996–1997
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653769/
https://www.ncbi.nlm.nih.gov/pubmed/19223901
http://dx.doi.org/10.1038/sj.bjc.6604934
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