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Rapamycin Induces Transactivation of the EGFR and Increases Cell Survival

The mammalian target of rapamycin (mTOR) signaling network regulates cell growth, proliferation and cell survival. Deregulated activation of this pathway is a common event in diverse human diseases such as cancers, cardiac hypertrophy, vascular restenosis, and nephrotic hypertrophy. Although mTOR in...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Deepti, Gao, Xianlong, Cohen, Micheal S., Taunton, Jack, Patel, Tarun B.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653860/
https://www.ncbi.nlm.nih.gov/pubmed/19151764
http://dx.doi.org/10.1038/onc.2008.490

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