Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives

[Image: see text] Herein we describe the construction of hexadecameric self-assembled dendrimers (SADs) using a series of dendronized 8-(m-acetylphenyl)-2′-deoxyguanosine (mAG) subunits. The azido-substituted mAG subunits were covalently linked to alkynyl polyester dendrons using a copper-catalyzed...

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Detalles Bibliográficos
Autores principales: Betancourt, José E., Rivera, José M.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654094/
https://www.ncbi.nlm.nih.gov/pubmed/18452304
http://dx.doi.org/10.1021/ol800701j
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author Betancourt, José E.
Rivera, José M.
author_facet Betancourt, José E.
Rivera, José M.
author_sort Betancourt, José E.
collection PubMed
description [Image: see text] Herein we describe the construction of hexadecameric self-assembled dendrimers (SADs) using a series of dendronized 8-(m-acetylphenyl)-2′-deoxyguanosine (mAG) subunits. The azido-substituted mAG subunits were covalently linked to alkynyl polyester dendrons using a copper-catalyzed 1,3-dipolar cycloaddition reaction. Discrete SADs are formed with high fidelity and thermal stability even with the increased steric hindrance offered by the dendrons.
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spelling pubmed-26540942009-03-20 Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives Betancourt, José E. Rivera, José M. Org Lett [Image: see text] Herein we describe the construction of hexadecameric self-assembled dendrimers (SADs) using a series of dendronized 8-(m-acetylphenyl)-2′-deoxyguanosine (mAG) subunits. The azido-substituted mAG subunits were covalently linked to alkynyl polyester dendrons using a copper-catalyzed 1,3-dipolar cycloaddition reaction. Discrete SADs are formed with high fidelity and thermal stability even with the increased steric hindrance offered by the dendrons. American Chemical Society 2008-05-02 2008-06-05 /pmc/articles/PMC2654094/ /pubmed/18452304 http://dx.doi.org/10.1021/ol800701j Text en Copyright © 2008 American Chemical Society http://pubs.acs.org This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org. 40.75
spellingShingle Betancourt, José E.
Rivera, José M.
Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives
title Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives
title_full Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives
title_fullStr Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives
title_full_unstemmed Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives
title_short Hexadecameric Self-Assembled Dendrimers Built from 2′-Deoxyguanosine Derivatives
title_sort hexadecameric self-assembled dendrimers built from 2′-deoxyguanosine derivatives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654094/
https://www.ncbi.nlm.nih.gov/pubmed/18452304
http://dx.doi.org/10.1021/ol800701j
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