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Total Synthesis of (±)-Actinophyllic Acid
[Image: see text] The first total synthesis of (±)-actinophyllic acid (1) is reported. Key steps of this synthesis include an intramolecular oxidative coupling of ketone and malonic ester enolates and an aza-Cope−Mannich rearrangement that assembled the core structure of the natural product’s unique...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654095/ https://www.ncbi.nlm.nih.gov/pubmed/18491907 http://dx.doi.org/10.1021/ja803158y |