Orally Available Selective Melanocortin-4 Receptor Antagonists Stimulate Food Intake and Reduce Cancer-Induced Cachexia in Mice

BACKGROUND: Cachexia is among the most debilitating and life-threatening aspects of cancer. It represents a metabolic syndrome affecting essential functional circuits involved in the regulation of homeostasis, and includes anorexia, fat and muscle tissue wasting. The anorexigenic peptide α-MSH is be...

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Detalles Bibliográficos
Autores principales: Weyermann, Philipp, Dallmann, Robert, Magyar, Josef, Anklin, Corinne, Hufschmid, Martina, Dubach-Powell, Judith, Courdier-Fruh, Isabelle, Henneböhle, Marco, Nordhoff, Sonja, Mondadori, Cesare
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654097/
https://www.ncbi.nlm.nih.gov/pubmed/19295909
http://dx.doi.org/10.1371/journal.pone.0004774

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