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Wld(S) requires Nmnat1 enzymatic activity and N16–VCP interactions to suppress Wallerian degeneration

Slow Wallerian degeneration (Wld(S)) encodes a chimeric Ube4b/nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1) fusion protein that potently suppresses Wallerian degeneration, but the mechanistic action of Wld(S) remains controversial. In this study, we characterize Wld(S)-mediated axon pr...

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Detalles Bibliográficos
Autores principales:	Avery, Michelle A., Sheehan, Amy E., Kerr, Kimberly S., Wang, Jing, Freeman, Marc R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654119/ https://www.ncbi.nlm.nih.gov/pubmed/19237597 http://dx.doi.org/10.1083/jcb.200808042

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