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One-dimensional topography underlies three-dimensional fibrillar cell migration

Current concepts of cell migration were established in regular two-dimensional (2D) cell culture, but the roles of topography are poorly understood for cells migrating in an oriented 3D fibrillar extracellular matrix (ECM). We use a novel micropatterning technique termed microphotopatterning (μPP) t...

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Detalles Bibliográficos
Autores principales: Doyle, Andrew D., Wang, Francis W., Matsumoto, Kazue, Yamada, Kenneth M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654121/
https://www.ncbi.nlm.nih.gov/pubmed/19221195
http://dx.doi.org/10.1083/jcb.200810041