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Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ
Telomeres protect chromosome ends from being viewed as double-strand breaks and from eliciting a DNA damage response. Deprotection of chromosome ends occurs when telomeres become critically short because of replicative attrition or inhibition of TRF2. In this study, we report a novel form of deprote...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654126/ https://www.ncbi.nlm.nih.gov/pubmed/19221198 http://dx.doi.org/10.1083/jcb.200810132 |