An Order of Magnitude Faster AIP1-Associated Actin Disruption than Nucleation by the Arp2/3 Complex in Lamellipodia

The mechanism of lamellipod actin turnover is still under debate. To clarify the intracellular behavior of the recently-identified actin disruption mechanism, we examined kinetics of AIP1 using fluorescent single-molecule speckle microscopy. AIP1 is thought to cap cofilin-generated actin barbed ends...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuji, Takahiro, Miyoshi, Takushi, Higashida, Chiharu, Narumiya, Shuh, Watanabe, Naoki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654150/
https://www.ncbi.nlm.nih.gov/pubmed/19290054
http://dx.doi.org/10.1371/journal.pone.0004921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654150/
https://www.ncbi.nlm.nih.gov/pubmed/19290054
http://dx.doi.org/10.1371/journal.pone.0004921

Ejemplares similares