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The Role of Genomic Data in the Discovery, Annotation and Evolutionary Interpretation of the Interferon-Lambda Family
BACKGROUND: Type-I interferons, type-II interferons, and the IL-10 family are helical cytokines with similar three-dimensional folds. However, their homologous relationship is difficult to detect on the basis of sequence alone. We have previously described the discovery of the human type-III interfe...
Autores principales: | Fox, Brian A., Sheppard, Paul O., O'Hara, Patrick J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654155/ https://www.ncbi.nlm.nih.gov/pubmed/19300512 http://dx.doi.org/10.1371/journal.pone.0004933 |
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