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Essential and unique roles of PIP5K-γ and -α in Fcγ receptor-mediated phagocytosis

The actin cytoskeleton is dynamically remodeled during Fcγ receptor (FcγR)-mediated phagocytosis in a phosphatidylinositol (4,5)-bisphosphate (PIP(2))-dependent manner. We investigated the role of type I phosphatidylinositol 4-phosphate 5-kinase (PIP5K) γ and α isoforms, which synthesize PIP(2), dur...

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Detalles Bibliográficos
Autores principales:	Mao, Yuntao S., Yamaga, Masaki, Zhu, Xiaohui, Wei, Yongjie, Sun, Hui-Qiao, Wang, Jing, Yun, Mia, Wang, Yanfeng, Di Paolo, Gilbert, Bennett, Michael, Mellman, Ira, Abrams, Charles S., De Camilli, Pietro, Lu, Christopher Y., Yin, Helen L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654300/ https://www.ncbi.nlm.nih.gov/pubmed/19153220 http://dx.doi.org/10.1083/jcb.200806121

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