Cognition, learning behaviour and hippocampal synaptic plasticity are not disrupted in mice over-expressing the cholesterol transporter ABCG1

BACKGROUND: Cognitive deficits are a hallmark feature of both Down Syndrome (DS) and Alzheimer's Disease (AD). Extra copies of the genes on chromosome 21 may also play an important role in the accelerated onset of AD in DS individuals. Growing evidence suggests an important function for cholest...

Descripción completa

Detalles Bibliográficos
Autores principales: Parkinson, Pamela F, Kannangara, Timal S, Eadie, Brennan D, Burgess, Braydon L, Wellington, Cheryl L, Christie, Brian R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654451/
https://www.ncbi.nlm.nih.gov/pubmed/19239689
http://dx.doi.org/10.1186/1476-511X-8-5

Ejemplares similares

Ejemplares similares