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Heparanase Regulates Levels of Syndecan-1 in the Nucleus
Syndecan-1 is a transmembrane heparan sulfate-bearing proteoglycan known to regulate multiple biological functions at the cell surface and within the extracellular matrix. Its functional activity can be modulated by heparanase, an enzyme that cleaves heparan sulfate chains and whose expression has b...
Autores principales: | Chen, Ligong, Sanderson, Ralph D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654539/ https://www.ncbi.nlm.nih.gov/pubmed/19305494 http://dx.doi.org/10.1371/journal.pone.0004947 |
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