The Oncogenic EWS-FLI1 Protein Binds In Vivo GGAA Microsatellite Sequences with Potential Transcriptional Activation Function

The fusion between EWS and ETS family members is a key oncogenic event in Ewing tumors and important EWS-FLI1 target genes have been identified. However, until now, the search for EWS-FLI1 targets has been limited to promoter regions and no genome-wide comprehensive analysis of in vivo EWS-FLI1 bind...

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Detalles Bibliográficos
Autores principales: Guillon, Noëlle, Tirode, Franck, Boeva, Valentina, Zynovyev, Andrei, Barillot, Emmanuel, Delattre, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654724/
https://www.ncbi.nlm.nih.gov/pubmed/19305498
http://dx.doi.org/10.1371/journal.pone.0004932

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