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Dual localization of wild-type myocilin in the endoplasmic reticulum and extracellular compartment likely occurs due to its incomplete secretion

PURPOSE: Wild-type myocilin is known to be secreted extracellularly, but a significant amount of the protein is also present in the endoplasmic reticulum (ER). The present study was undertaken to address whether intracellular myocilin is a true ER resident protein. METHODS: Human wild-type myocilin...

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Detalles Bibliográficos
Autores principales: Sohn, Seongsoo, Joe, Myung Kuk, Kim, Tae Eun, Im, Ji-eun, Choi, Young Ran, Park, Hwayong, Kee, Changwon
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654785/
https://www.ncbi.nlm.nih.gov/pubmed/19287508

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