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Dual localization of wild-type myocilin in the endoplasmic reticulum and extracellular compartment likely occurs due to its incomplete secretion
PURPOSE: Wild-type myocilin is known to be secreted extracellularly, but a significant amount of the protein is also present in the endoplasmic reticulum (ER). The present study was undertaken to address whether intracellular myocilin is a true ER resident protein. METHODS: Human wild-type myocilin...
Autores principales: | Sohn, Seongsoo, Joe, Myung Kuk, Kim, Tae Eun, Im, Ji-eun, Choi, Young Ran, Park, Hwayong, Kee, Changwon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654785/ https://www.ncbi.nlm.nih.gov/pubmed/19287508 |
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