Cargando…
‘Double water exclusion’: a hypothesis refining the O-ring theory for the hot spots at protein interfaces
Motivation: The O-ring theory reveals that the binding hot spot at a protein interface is surrounded by a ring of residues that are energetically less important than the residues in the hot spot. As this ring of residues is served to occlude water molecules from the hot spot, the O-ring theory is al...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654803/ https://www.ncbi.nlm.nih.gov/pubmed/19179356 http://dx.doi.org/10.1093/bioinformatics/btp058 |