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High-Throughput Proteomics Detection of Novel Splice Isoforms in Human Platelets
Alternative splicing (AS) is an intrinsic regulatory mechanism of all metazoans. Recent findings suggest that 100% of multiexonic human genes give rise to splice isoforms. AS can be specific to tissue type, environment or developmentally regulated. Splice variants have also been implicated in variou...
Autores principales: | Power, Karen A., McRedmond, James P., de Stefani, Andreas, Gallagher, William M., Ó Gaora, Peadar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654914/ https://www.ncbi.nlm.nih.gov/pubmed/19308253 http://dx.doi.org/10.1371/journal.pone.0005001 |
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