Coordinated Activation of Candidate Proto-Oncogenes and Cancer Testes Antigens via Promoter Demethylation in Head and Neck Cancer and Lung Cancer

BACKGROUND: Epigenetic alterations have been implicated in the pathogenesis of solid tumors, however, proto-oncogenes activated by promoter demethylation have been sporadically reported. We used an integrative method to analyze expression in primary head and neck squamous cell carcinoma (HNSCC) and...

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Detalles Bibliográficos
Autores principales: Smith, Ian M., Glazer, Chad A., Mithani, Suhail K., Ochs, Michael F., Sun, Wenyue, Bhan, Sheetal, Vostrov, Alexander, Abdullaev, Ziedulla, Lobanenkov, Victor, Gray, Andrew, Liu, Chunyan, Chang, Steven S., Ostrow, Kimberly L., Westra, William H., Begum, Shahnaz, Dhara, Mousumi, Califano, Joseph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654921/
https://www.ncbi.nlm.nih.gov/pubmed/19305507
http://dx.doi.org/10.1371/journal.pone.0004961

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