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Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation
Heterochromatin contains many repetitive DNA elements and few protein-encoding genes, yet it is essential for chromosome organization and inheritance. Here, we show that Drosophila that lack the Su(var)3-9 H3K9 methyltransferase display significantly elevated frequencies of spontaneous DNA damage in...
Autores principales: | Peng, Jamy C., Karpen, Gary H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654965/ https://www.ncbi.nlm.nih.gov/pubmed/19325889 http://dx.doi.org/10.1371/journal.pgen.1000435 |
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